Growing human retinal organoids to understand development of the human eye

Study of Optical Models Regarding the Human Eye

Introduction: Until now, many models have been presented for optical study of the human eye. In recent years, surgery on the anterior section of the eye (such as cataract and photo-refractive surgery) has increased, so a study on the optics of the eye and evaluation of vision quality has become more important. Material and Methods: In this article, some of these models are considered. They incl...

The Development of the Human Eye

Human hepatic organoids for the analysis of human genetic diseases.

We developed an in vitro model system where induced pluripotent stem cells (iPSCs) differentiate into 3-dimensional human hepatic organoids (HOs) through stages that resemble human liver during its embryonic development. The HOs consist of hepatocytes, and cholangiocytes, which are organized into epithelia that surround the lumina of bile duct-like structures. The organoids provide a potentiall...

Aberrations and retinal image quality of the normal human eye.

We have constructed a wave-front sensor to measure the irregular as well as the classical aberrations of the eye, providing a more complete description of the eye's aberrations than has previously been possible. We show that the wave-front sensor provides repeatable and accurate measurements of the eye's wave aberration. The modulation transfer function of the eye computed from the wave-front s...

Dynamic retinal image reconstruction of the human eye

Human visual performance is usually measured by conventional techniques (eg. letter charts), which cannot provide complete information of what a person actually sees in complex scenes. This paper considers reconstruction of the retinal image for real-world scenes based on the monochromatic aberrations of the human eye. Such aberrations can be evaluated by using an aberroscope or a Hartmann-Shac...